A phase 1 clinical trial of long-term, low-dose treatment of WHIM syndrome with the CXCR4 antagonist plerixafor
2014; Elsevier BV; Volume: 123; Issue: 15 Linguagem: Inglês
10.1182/blood-2013-09-527226
ISSN1528-0020
AutoresDavid H. McDermott, Qian Liu, Daniel Velez, Lizbeeth Lopez, Sandra Anaya‐O’Brien, Jean Ulrick, Nana Kwatemaa, Judy Starling, Thomas A. Fleisher, Debra A. Long Priel, Melissa A. Merideth, Robert Giuntoli, Moses O. Evbuomwan, Patricia Littel, Martha Marquesen, Dianne Hilligoss, Rosamma DeCastro, George Grimes, Samuel Hwang, Stefania Pittaluga, Katherine R. Calvo, Pamela Stratton, Edward W. Cowen, Douglas B. Kuhns, Harry L. Malech, Philip M. Murphy,
Tópico(s)Immunotherapy and Immune Responses
ResumoKey Points Plerixafor can be given safely to WHIM syndrome patients twice daily for a 6-month period and appears promising as a treatment.
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