Hereditary Nonspherocytic Hemolytic Anemia Due to Pyruvate Kinase Deficiency: A Prevalence Study in Quebec (Canada)
1992; Karger Publishers; Volume: 42; Issue: 3 Linguagem: Inglês
10.1159/000154063
ISSN1423-0062
AutoresEveline de Médicis, Peter Ross, Ronald J. Friedman, Heather Hume, Danielle J. Marceau, Marcel Milot, J Lyonnais, Marc De Braekeleer,
Tópico(s)Blood groups and transfusion
ResumoFifty-eight cases of hereditary nonspherocytic hemolytic anemia due to pyruvate kinase deficiency were collected from both laboratories that have performed the assay since 1972 and from attending physicians in the province of Quebec. Using the postal addresses of the probands, a prevalence map was constructed according to the administrative regions of the province of Quebec. The prevalence was found to be higher in eastern Quebec (1/81,838) than in western Quebec (1/139,086). Fifty probands were of French Canadian origin whereas the remaining 6 were recent immigrants.
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