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Fluid Management With a Simplified Conservative Protocol for the Acute Respiratory Distress Syndrome*

2014; Lippincott Williams & Wilkins; Volume: 43; Issue: 2 Linguagem: Inglês

10.1097/ccm.0000000000000715

1530-0293

Colin K. Grissom, Eliotte L. Hirshberg, Justin B. Dickerson, Samuel M. Brown, Michael J. Lanspa, Kathleen D. Liu, David Schoenfeld, Mark Tidswell, R. Duncan Hite, Peter Rock, Russell R. Miller, Alan H. Morris, L. D. HUDSON, S. Gundel, C.T. Hough, Margaret J. Neff, Kevin Sims, Anna Ungar, Timothy R. Watkins, Jay S. Steingrub, Mark Tidswell, E. Braden, L. DeSouza, J. F. Germain, Cynthia Kardos, Denise Kelley, Lori Kozikowski, S. Ouellette, Kalpalatha K. Guntupalli, Venkata Bandi, C. Pope, Catherine Ross, Roy G. Brower, H Fessler, David N. Hager, Pedro A. Mendez-Tellez, Dale M. Needham, K. Oakjones, Jonathan Sevransky, A. Workneh, Carl Shanholtz, Daniel J. Herr, H. Howes, Giora Netzer, Peter Rock, Aline Menezes Sampaio, J. Titus, Peter J. Sloane, T. Beck, H. Highfield, Susan King, Benjamin Lee, N. Bolouri, Herbert Wiedemann, Rendell W. Ashton, D.A. Culver, Terri M. Frederick, J. A. Guzmán, J. J. Komara, Anita Reddy, Rana Hejal, M. Andrews, David J. Haney, Alfred F. Connors, S. Lasalvia, J. Daryl Thornton, Edward Warren, Mark Moss, Ellen L. Burnham, Lincoln Gray, James P. Maloney, Meredith Mealer, Ivor S. Douglas, Katherine H. Overdier, Kelly Thompson, Robert Wolken, S K Frankel, Jeffrey McKeehan, M. L. Warner, T. Bost, C. Higgins, Katherine Hodgin, Neil R. MacIntyre, Lisa M. Brown, Christopher E. Cox, Michael A. Gentile, Joseph A. Govert, Nancy W. Knudsen, Shannon S. Carson, Lydia Chang, Summer Choudhury, Wendy L. Hall, Joyce Lanier, Arthur P. Wheeler, G R Bernard, Matthew R. Hays, Saruveish Mogan, Todd W. Rice, R. Duncan Hite, K. Bender, Andrea Harvey, Peter E. Morris, Mary Ragusky, Patrick E. Wright, S. Groce, Jessica McLean, A. Overton, Jonathon D. Truwit, Kyle B. Enfield, Michael S. Marshall, Alan H. Morris, Andrea Austin, S. Barney, Samuel M. Brown, John G. Ferguson, H. Gallo, T. Graydon, Colin K. Grissom, Eliotte L. Hirshberg, Al Jephson, Naresh Kumar, C. Ryan Miller, David J. Murphy, James F. Orme, Ann Stowe, L. Struck, Fridtjof Thomas, Donald J. Ward, Liam Weaver, Polly Bailey, William Beninati, L. Bezdijan, T. P. Clemmer, S. Rimkus, R. Tanaka, C. Lawton, D. Hanselman, Krishna M. Sundar, William T. Alward, Christine E. Bishop, D. Eckley, T. W. Hill, Brian C. Jensen, K. Ludwig, Dorthe Viemose Nielsen, Michael J. Pearce, Michael A. Matthay, Carolyn S. Calfee, B. Daniel, Mark D. Eisner, Óscar García, Kristina Kordesch, K. Liu, N. Shum, Hanjing Zhou, Michael W. Peterson, Jurre Blaauw, K. Van Gundy, Timothy E. Albertson, Brian M. Morrissey, E. Vlastelin, Rolf D. Hubmayr, D Brown, Marc J. Dubin, Emir Festić, Ognjen Gajic, Richard Hinds, Steven R Holets, Daryl J. Kor, A. Lee, Melissa Passe, Graham Simpson, James R. Wright, Ben deBoisblanc, Andreya Antoine, D. Charbonnet, Joanne H. Hunt, P. Lauto, Alan B. Marr, G. Meyaski, Connie Romaine, Reyes Tejedor, S. Brierre, James D. Byrne, Tonya Jagneaux, C. LeBlanc, Karine Moreau, Charles R. Thomas, Sumeet Jain, David McD Taylor, Leonardo Seoane, C.J. Hebert, Joanne Thompson, Francesco Simeone, J. Fearon, David Schoenfeld, Moytrayee Guha, Elizabeth Hammond, Nuala-Jane Lavery, P. Lazar, Robert L. Morse, Cathryn F. Oldmixon, Nancy Ringwood, Elizabeth W. Smoot, Bruce Thompson, Roger S. Wilson, Andrea L. Harabin, S. Bredow, M A Waclawiw, Gail Weinmann,

Trauma, Hemostasis, Coagulopathy, Resuscitation

In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outcomes than a liberal fluid protocol (FACTT Liberal). Subsequent Acute Respiratory Distress Syndrome Network studies used a simplified conservative fluid protocol (FACTT Lite). The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols.