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Towards fabrication of 3D printed medical devices to prevent biofilm formation

2013; Elsevier BV; Volume: 459; Issue: 1-2 Linguagem: Inglês

10.1016/j.ijpharm.2013.11.001

1873-3476

Niklas Sandler, Ida Salmela, Adyary Fallarero, Ari Rosling, Mohammad Khajeheian, Ruzica Kolakovic, Natalja Genina, Johan Nyman, Pia Vuorela,

Bacterial biofilms and quorum sensing

The use of three-dimensional (3D) printing technologies is transforming the way that materials are turned into functional devices. We demonstrate in the current study the incorporation of anti-microbial nitrofurantoin in a polymer carrier material and subsequent 3D printing of a model structure, which resulted in an inhibition of biofilm colonization. The approach taken is very promising and can open up new avenues to manufacture functional medical devices in the future.