Platelet peripheral benzodiazepine receptors in repeated stress
1991; Elsevier BV; Volume: 48; Issue: 4 Linguagem: Inglês
10.1016/0024-3205(91)90554-o
ISSN1879-0631
AutoresDalit E. Dar, Abraham Weizman, Leon Karp, Alexander Grinshpoon, Miri Bidder, Moshe Kotler, Sam Tyano, Avraham Bleich, Moshe Gavish,
Tópico(s)Adipose Tissue and Metabolism
Resumo[3H]PK 11195 binding to platelet membranes and plasma stress hormones were studied in soldiers at the beginning of a parachute training course, following 6 days of preparatory exercises, and after the fourth actual parachute jump. A slight reduction (15%; NS in the number of peripheral benzodiazepine receptors (PBR) was detected at the end of the exercise period, prior to the first jump. Reduced (26%; P<0.05) density of PBR was observed immediately after the repeated actual jumps. Equilibrium dissociation constants were not affected by the stressful situation. Plasma cortisol and prolactin levels remained unaltered during the entire study period.
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