Artigo Acesso aberto Revisado por pares

EFFECTS OF A POTENT AND SPECIFIC β 2 ‐ADRENOCEPTOR ANTAGONIST ON INTRAOCULAR PRESSURE

1981; Wiley; Volume: 73; Issue: 1 Linguagem: Inglês

10.1111/j.1476-5381.1981.tb16776.x

ISSN

1476-5381

Autores

James A. Nathanson,

Tópico(s)

Photoreceptor and optogenetics research

Resumo

Physiological studies support the possibility of adrenergic regulation of aqueous humor secretion from the ciliary process, a tissue which has recently been shown to contain a predominance of β 2 ‐adrenoceptors. The present experiments examine the effects of a potent and highly specific β 2 ‐antagonist (IPS 339) on intraocular pressure in the normal rabbit eye. The observed decrease in pressure caused by IPS 339 suggests that highly specific β 2 ‐antagonists may be useful in decreasing elevated intraocular pressure.

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