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Genetic analysis of the concentrations of pyrrolizidine alkaloids in Senecio jacobaea

1993; Elsevier BV; Volume: 32; Issue: 5 Linguagem: Inglês

10.1016/s0031-9422(00)95079-9

1873-3700

Klaas Vrieling, Hélène de Vos, Catharina A. M. van der Veen‐van Wijk,

Drug-Induced Hepatotoxicity and Protection

We investigated whether the large phenotypic variation in pyrrolizidine alkaloid (PA) concentration in Senecio jacobaea has a genetic component. A diallel cross and a half-sib analysis showed that 50–100% of the total variation in total PA concentration is due to genetic differences in the laboratory. For a large number of the major individual PAs significant heritabilities (for concentration as well as composition) were found in a nutrient-stressed and drought-stressed environment in half-sib analyses. PA concentrations differed significantly between the nutrient and drought treatments.