Artigo Revisado por pares

New Sakaguchi reaction

1965; Elsevier BV; Volume: 10; Issue: 2 Linguagem: Inglês

10.1016/0003-2697(65)90262-9

ISSN

1096-0309

Autores

Yoshiharu Izumi,

Tópico(s)

Chemical Synthesis and Reactions

Resumo

The Sakaguchi reaction for arginine has been improved by pretreatment of amino acid mixtures with acetic anhydride to block amino groups. The advantages of this method are: (1) the color produced by the Sakaguchi reaction is stabilized; (2) optimum conditions for the Sakaguchi reaction are easily maintained; (3) a reliable standard curve can be produced. Some amino acids containing reduced groups (histidine, methionine, tryptophan, tryrosine) remain and inhibit the Sakaguchi reaction.

Referência(s)