Fast production of highly concentrated reactive [18F] fluoride for aliphatic and aromatic nucleophilic radiolabelling
2009; Elsevier BV; Volume: 51; Issue: 1 Linguagem: Inglês
10.1016/j.tetlet.2009.10.085
ISSN1873-3581
AutoresJoël Aerts, Samuël Voccia, Christian Lemaire, Fabrice Giacomelli, David Goblet, David Thonon, Alain Plenevaux, Geoffrey Warnock, André Luxen,
Tópico(s)Chemical Reactions and Isotopes
ResumoThe use of a polymeric solid support loaded with a long alkyl chain quaternary ammonium allows the rapid and efficient recovery of cyclotron produced [18F]F− from [18O]water to a low water content organic solution compatible with fast nucleophilic labelling of most precursors for PET radiopharmaceuticals in high yield.
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