Application of imiquimod by suppositories (anal tampons) efficiently prevents recurrences after ablation of anal canal condyloma
2002; Oxford University Press; Volume: 147; Issue: 4 Linguagem: Inglês
10.1046/j.1365-2133.2002.04979.x
ISSN1365-2133
AutoresM. Kaspari, Ralf Gutzmer, T. Kaspari, Alexander Kapp, Jens P. Brodersen,
Tópico(s)Urologic and reproductive health conditions
ResumoSummary Background After surgical removal, anal canal condyloma (ACC) has a higher risk of recurrence compared with extragenital warts. Objectives To reduce local recurrences of ACC using follow-up treatment with imiquimod-containing suppositories (anal tampons). Methods After ablation of ACC, 10 male patients received treatment with imiquimod suppositories three times weekly for 3–4 months. Results Treatment with imiquimod anal tampons was well tolerated. Early initial recurrences in some patients cleared after treatment with the imiquimod suppositories. Within a mean follow-up of 9 months no patient demonstrated recurrence of ACC. Conclusions These data suggest that imiquimod anal tampons may represent a new therapeutic option to prevent recurrences of ACC following ablative surgery.
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