SUSTAINED PROTECTION FROM PENTAVALENT ROTAVIRUS VACCINATION DURING THE SECOND YEAR OF LIFE AT A LARGE, URBAN UNITED STATES PEDIATRIC HOSPITAL
2010; Lippincott Williams & Wilkins; Volume: 29; Issue: 12 Linguagem: Inglês
10.1097/inf.0b013e3181ed18ab
ISSN1532-0987
AutoresJulie A. Boom, Jacqueline E. Tate, Leila C. Sahni, Marcia A. Rench, Osbourne Quaye, Slavica Mijatovic-Rustempasic, Manish M. Patel, Carol J. Baker, Umesh D. Parashar,
Tópico(s)Viral Infections and Immunology Research
ResumoFecal specimens from children presenting to Texas Children's Hospital with acute gastroenteritis were tested for the presence of rotavirus. Children were grouped according to vaccination status, and pentavalent rotavirus vaccine effectiveness was calculated. Pentavalent rotavirus vaccine effectiveness against severe rotavirus gastroenteritis was sustained during the first 2 years of the vaccination program. Overall 3-dose effectiveness was 83% to 86%; it was 92% to 93% among children 6 to 11 months of age and 78% to 84% among children ≥12 months of age.
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