Artigo Revisado por pares

Total Synthesis of (+)-Arteanniun M Using the Tandem Oxy-Cope/Ene Reaction

2001; American Chemical Society; Volume: 3; Issue: 12 Linguagem: Inglês

10.1021/ol015970l

ISSN

1523-7060

Autores

Louis Barriault, Daniel H. Deon,

Tópico(s)

Synthetic Organic Chemistry Methods

Resumo

The first total synthesis of (+)-arteannuin M was accomplished using the tandem oxy-Cope/transannular ene reaction as the key step to construct the bicyclic core of the natural product. The tandem reaction proceeded with high diastereo- and enantiomeric excess.

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