Artigo Revisado por pares

Novel Antioxidant Therapy for Cerebral Ischemia‐Reperfusion Injury

1994; Wiley; Volume: 723; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1994.tb36730.x

ISSN

1749-6632

Autores

Jill A. Panetta, James A. Clemens,

Tópico(s)

Electron Spin Resonance Studies

Resumo

Annals of the New York Academy of SciencesVolume 723, Issue 1 p. 239-245 Novel Antioxidant Therapy for Cerebral Ischemia-Reperfusion Injury JILL ANN PANETTA, JILL ANN PANETTA Lilly Research Laboratories (DC 0444) Lilly Corporate Center Indianapolis, Indiana 46285Search for more papers by this authorJAMES A. CLEMENS, JAMES A. CLEMENS Lilly Research Laboratories (DC 0444) Lilly Corporate Center Indianapolis, Indiana 46285Search for more papers by this author JILL ANN PANETTA, JILL ANN PANETTA Lilly Research Laboratories (DC 0444) Lilly Corporate Center Indianapolis, Indiana 46285Search for more papers by this authorJAMES A. CLEMENS, JAMES A. CLEMENS Lilly Research Laboratories (DC 0444) Lilly Corporate Center Indianapolis, Indiana 46285Search for more papers by this author First published: June 1994 https://doi.org/10.1111/j.1749-6632.1994.tb36730.xCitations: 7AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Traystman, R. J., J. R. Kirsch & R. C. Koehler. 1991. Oxygen radical mechanisms of brain injury following ischemia and reperfusion. J. Appl. Physiol. 71: 1185– 1195. 2 Jesberger, J. A. & J. S. Richardson. 1991. Oxygen free-radicals and brain dysfunction. Int. J. Neurosci. 57: 1– 17. 3 Aust, S. D., L. A. Morehouse & C. E. Thomas. 1985. Role of metals in oxygen radical reactions. J. Free Radic. Biol. Med. 1: 3. 4 Halliwell, B. 1989. Oxidants and the central nervous system: some fundamental questions. Is oxidant damage relevant to Parkinson's Disease, Alzheimer's Disease, traumatic injury or stroke? Acta Neurol. Scand. 126: 23– 33. 5 Halliwell, B. & J. M. C. Gutteridge. 1985. Lipid peroxidation: a radical chain reaction. In Free Radicals in Biology and Medicine. p. 139. Clarendon Press. Oxford . 6 Yoshida, S., K. Abe, R. Busro, B. D. Watson, K. Kogure & M. D. Ginsberg, 1982. Influence of transient ischemia on lipid soluble antioxidants, free fatty-acids and energy metabolites in rat brain. Brain Res. 245: 307– 316. 7 Bromont, C., C. Marie & J. Bralet. 1989. Increased lipid peroxidation in vulnerable brain regions after transient forebrain ischemia in rats. Stroke 20: 918– 924. 8 Sakamoto, A., S. T. Ohnishi, T. Ohnishi & R. Ogawa. 1991. Relationship between free radical production and lipid peroxidation during ischemia-reperfusion injury in the rat brain. Brain Res. 554: 186– 192. 9 Yue, T.-L., J.-L. Gu, P. L. Lysko, H. Y. Cheng, F. C. Barone & G. Feuerstein. 1992. Neuroprotective effects of phenyl-t-butyl-nitrone in gerbil global brain ischemia and in cultured rat cerebellar neurons. Brain Res. 574: 193– 197. 10 Martz, D., G. Rayos, G. P. Schielke & A. L. Betz. 1989. Allopurinol and dimethyithiourea reduce brain infarction following middle cerebral artery occlusion in rats. Stroke 20: 488– 494. 11 Panetta, J. A., M. L. Phillips, K. Wolski & J. A. Clemens. 1990. Effects of two inhibitors of lipid peroxidation on ischemic brain damage. In Pharmacology of Cerebral Ischemia. J. Krieglstin & H. Oberpichler, Eds: 351– 356. Wissenschaftliche Verlagsgesell-schaft. Stuttgart . 12 Hall, E. D. 1988. Effects of the 21-aminosteroid U74006F on posttraumatic spinal cord ischemia in cats. J. Neurosurg. 68: 462– 465. 13 Hall, E. D., K. E. Pazara & M. J. Braughler. 1988. 21-Aminosteroid lipid peroxidation inhibitor U74006F protects against cerebral ischemia in gerbils. Stroke 19: 997– 1002. 14 Armstead, W. M., R. Mirro, O. P. Thelin, M. Shibata, S. L. Zuckerman, D. R. Shanklin, D. W. Busija & C. W. Leffler. 1992. Polyethylene glycol superoxide dismutase and catalase attenuate increased blood-brain barrier permeability after ischemia in piglets. Stroke 23(5): 755– 762. 15 Beckman, J. S., T. H. Liu, E. L. Hogan, S. L. Lindsay, B. A. Freeman & C. Y. Hsu. 1989. Evidence for a role of oxygen radicals in cerebral ischemic injury. In Cerebrovascular Diseases. M. D. Ginsberg & W. D. Dietrich, Eds.: 373– 380. Raven Press. New York . 16 Panetta, J. A., D. N. Benslay, M. L. Phillips, R. D. Towner, B. Bertsch, L. Wang & P. P. K. Ho. 1989. The anti-inflammatory effects of LY178002 and LY256548. Agents Actions 27: 300– 302. 17 Pulsinelli, W. A. & J. B. Brierley. 1979. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 10: 267– 272. 18 Clemens, J. A., R. D. Saunders, P. P. Ho, L. A. Phebus & J. A. Panetta. 1993. The antioxidant LY231617 reduces global ischemic neuronal injury in rats. Stroke 24: 716– 723. 19 O'keefe, J. & L. Nadel. 1978. The Hippocampus as a Cognitive Map. Oxford University Press. New York . 20 Becker, J. T., J. A. Walker & D. Olton. 1980. Neuroanatomical bases of spatial memory. Brain Res. 200: 307– 320. 21 Winson, J. 1978. Loss of hippocampal theta rhythm results in spatial memory deficit in the rat. Science 201: 160– 163. 22 Mcnaughton, B., C. Barnes, G. Rao, J. Baldwin & M. Basmussen. 1986. Long-term enhancement of hippocampal synaptic transmission and the acquisition of spatial information. Neurosci. 6: 563– 571. 23 Davis, H. P., J. Tribuna, W. A. Pulsinelli & B. T. Volpe. 1986. Reference and working memory of rats following hippocampal damage induced by transient forebrain ischemia. Physiol. Behav. 37: 387– 392. 24 Volpe, B. T., B. Waczek & H. P. Davis. 1988. Modified T-maze training demonstrates dissociated memory loss in rats with ischemic hippocampal injury. Behav. Brain Res. 27: 259– 268. 25 Monmaur, P., M. A. Thomson & M. M'harzi. 1986. Temporal changes in hippocampal theta activity following twenty minutes of forebrain ischemia in the chronic rat. Brain Res. 378: 262– 273. 26 Monmaur, P., M. Allix, D. Schoenaert-Brossault, O. Houcine, M. Plotkine & F. Willig. 1990. Effects of transient cerebral ischemia on the hippocampal dentate theta profile in the acute rat: a study 4–5 months following recirculation. Brain Res. 508: 124– 134. Citing Literature Volume723, Issue1Cellular, Biochemical, and Molecular Aspects of Reperfusion InjuryJune 1994Pages 239-245 ReferencesRelatedInformation

Referência(s)