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Inhalation Studies with Chloracetophenone, Diphenylaminochloroarsine, and Pelargonic Morpholide—I. Animal Exposures

1962; Taylor & Francis; Volume: 23; Issue: 3 Linguagem: Inglês

10.1080/00028896209342853

2163-369X

Charles L. Punte, Thomas A. Ballard, John T. Weimer,

Pesticide Exposure and Toxicity

Abstract Acute toxicity studies in rats, mice, and guinea pigs indicate that chloracetophenone, diphenylaminochloroarsine, and pelargonic morpholide are slightly to moderately toxic materials. The signs of intoxication observed in the animals during the exposure to these compounds were salivation, lacrimation, lethargy and labored breathing. Histopathological examination of animals sacrificed or dying during exposure revealed no findings below an inhaled dose of 1,000 mg-min/M3 of chloracetophenone, 500 mg-mia/M2 of diphenylaminochloroarsine, and 5,000 mg-mitt/M2 of pelargonic morpholide.