Portal de Periódicos da CAPES

Artigo Acesso aberto Produção Nacional Revisado por pares

BIBTEX RIS

Avaliação histopatológica dos efeitos colaterais do uso intraestromal de biguanida em córnea de coelhos

2010; Sociedade Brasileira de Oftalmologia; Volume: 69; Issue: 6 Linguagem: Inglês

10.1590/s0034-72802010000600004

1982-8551

Lucas Vieira Bueno Rossi, Eduardo Vieira Braga Espindola, Wilson Nahmatallah Obeid, Fernando Buzatto Montovan, Leonardo Guedes Candido Marculino, Vanessa Takayama, Moacyr Pezati Rigueiro, Denise de Freitas, Luiz Antônio Vieira,

Glaucoma and retinal disorders

PURPOSE: Observe the effects of corneal intrastromal injection of biguanide at 0.02%, 0.1% and 0.5% in rabbits’ eyes. METHODS: Doble blind prospective study. 8 rabbits were used, randomly identified and divided into 4 groups, with 2 rabbits each, with the administration of 0.2 ml of the drug via intrastromal, in the right eye. The first group received biguanide at a concentration of 0.02%, the second one at 0.1%, the third at 0.5% and the fourth group (control) was given a [...]