A SERIES OF CASES OF CONGENITAL OPHTHALMOPLEGIA EXTERNA (NUCLEAR PARALYSIS) IN THE SAME FAMILY
1910; BMJ; Volume: 1; Issue: 2572 Linguagem: Inglês
10.1136/bmj.1.2572.917
ISSN0959-8138
Autores Tópico(s)Craniofacial Disorders and Treatments
Resumo^IL S6 I9IO.]CONGENITALOVATHALMOPLE6IA EYTERINA.' 7 ,, [ . . . ..~~~~~~~~~~~~~~~~~~~~~~~~~~~,,I phlyetenule itself io of tuberculous histological structuresor that it contains the tubercle bacillus.Nevertheless, it is now widely believed that, practically speaking, the characteristic lesion occurs only in those who are the -subjects of tuberculosis, latent or otherWise.The main facts that have led to this change of opinion are:1.The frequency with which -a -family .history* of tubercle can be obtained from the subjects of phlyetenular -disease.2. The frequent coexistence, along with phlyctenular 'disease, of ottier manifestations of tuberculosis as, for ,example, enlarged glands -or joints, otorrhoea with or without mastoid disease, phthisis pulmonalis, dactylitis, ,and scrofalodermia.3. The fact, as shown by the experimental work of J. B. Nias and Leslie Paton,' that the blood of patients suIffering from phlyctenular discase behaves in a manner which is typical of a definite tuberculous infection.As the result of examination of the blood in upwards of *fifty patients with phlyetenular disease, these authors claim that their observations of the opsonic index go far -to support the hypothesis that phlyetenular ulcers are due '4o the escape of attenuated or dead bacilli from some ,distant focas, identified or otherwise, of tuberculous disease.4. The positive result obtained in phlyctenular cases by employing the Koch, Wolff-Eisner-Calmette, von i'irquet, or otlher specific test for tubercle (Stephenson, Derby, Weekers, etc.).
Referência(s)