Sarcosine oxidase activity of rat liver tissue: Effect of folic acid deficiency and induced hyperthyroidism
1952; Elsevier BV; Volume: 41; Issue: 1 Linguagem: Inglês
10.1016/0003-9861(52)90512-2
ISSN1096-0384
AutoresMarian E. Swendseid, Ann L. Swanson, Frank H. Bethell,
Tópico(s)Vitamin C and Antioxidants Research
ResumoThe sarcosine oxidase content of hepatic tissue from rats made deficient in folic acid was similar to that of normal rats. This is taken as evidence that sarcosine oxidase activity is not dependent upon the presence of folic acid vitamins. The liver sarcosine content of vitamin B12-deficient rats was decreased below normal values. Since B12 supplementation did not increase the enzyme activity, it could not be ascertained whether the loss in enzyme activity was primarily due to a B12 deficiency or whether it was the result of other conditions imposed by a hyperthyroid state.
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