Artigo Produção Nacional Revisado por pares

15 STR loci frequencies with mutation rates in the population from Rio Grande do Sul, Southern Brazil

2008; Elsevier BV; Volume: 3; Issue: 2 Linguagem: Inglês

10.1016/j.fsigen.2008.05.006

ISSN

1878-0326

Autores

Fernanda Goulart Lanes Chula, Rodrigo Rodenbusch, Simone Schumacher, Tarciana Grandi, Candice Tosi Michelon, André Zoratto Gastaldo, Cíntia Costi, Bianca A. Carvalho, Cláudia Maria Dornelles da Silva,

Tópico(s)

Genetic diversity and population structure

Resumo

Allele frequencies for 15 short tandem repeats (STR) loci were obtained from a sample of 2038 individuals undergoing paternity testing. The population is from Rio Grande do Sul, Brazil. The loci are the most commonly used in forensic and paternity testing, being analysed by the AmpFlSTR Identifiler (Applied Biosystems) commercial kit. The most polymorphic locus was D2S1338. Mutation rates were ascertained from this population sample. All the loci analysed reached the Hardy-Weinberg equilibrium. The results of genetic distance are consistent with the European-derived origins of Rio Grande do Sul population.

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