Coordinated Polar Localization of Auxin Efflux Carrier PIN1 by GNOM ARF GEF
1999; American Association for the Advancement of Science; Volume: 286; Issue: 5438 Linguagem: Inglês
10.1126/science.286.5438.316
ISSN1095-9203
AutoresThomas Steinmann, Niko Geldner, Markus Grebe, Stefan Mangold, Catherine Jackson, S Paris, Leo Gälweiler, Klaus Palme, Gerd Jürgens,
Tópico(s)Plant nutrient uptake and metabolism
ResumoThe plant hormone auxin is transported in a polar manner along the shoot-root axis, which requires efflux carriers such as PIN1. Asymmetric localization of PIN1 develops from a random distribution in Arabidopsis early embryogenesis. Coordinated polar localization of PIN1 is defective in gnom embryos. GNOM is a membrane-associated guanine-nucleotide exchange factor on ADP-ribosylation factor G protein (ARF GEF). Thus, GNOM-dependent vesicle trafficking may establish cell polarity, resulting in polar auxin transport.
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