Voltar
Artigo Revisado por pares
BIBTEX RIS

Localized exogenous ochronosis

1983; Elsevier BV; Volume: 8; Issue: 6 Linguagem: Inglês

10.1016/s0190-9622(83)80022-x

ISSN

1097-6787

Autores

David A. Cullison, Donald C. Abele, James L. O’Quinn,

Tópico(s)

Skin Protection and Aging

Resumo

A 58-year-old black woman with localized exogenous ochronosis due to the use of a proprietary hydroquinone bleaching cream is described. Histologic studies, including electron microscopy, are presented. The differential diagnosis of blue-black hyperpigmentation is discussed. The literature on ochronosis, both endogenous (alkaptonuria) and exogenous, is reviewed, and a unifying theory for the formation (from hydroquinones) of hydroxylated indoles similar to melanin precursors is outlined.

Referência(s)