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Hemoglobin Karatsu: Beta 120 (GH 3) Lysinc → Asparaine, an Example of Hb Riyadh in Japan

1977; Taylor & Francis; Volume: 1; Issue: 5 Linguagem: Inglês

10.3109/03630267709027863

1532-432X

T Miyaji, Yusuke Ohba, M. Matsunka, Hironori Kudoh, Masahide Asano, K. Yamaoto, Toru Satoh,

Neonatal Health and Biochemistry

Hemoglobin Karatsu was discovered in a Japanese male during a random survey of patients. Fingerprints of aminoethylated beta chain revealed an abnormal beta Tp12B-13 spot. Further chemical analyses and comparison with the corresponding tryptic peptide from Hb Hijiyama demonstrated an identical amino acid substitution with Hb Riyadh.