Origin and Biologic Individuality of the Genetic Dictionary
1962; American Association for the Advancement of Science; Volume: 138; Issue: 3547 Linguagem: Inglês
10.1126/science.138.3547.1328
ISSN1095-9203
AutoresDario Giacomoni, S. Spiegelman,
Tópico(s)Genomics and Chromatin Dynamics
ResumoDeoxyribonucleic acid contains sequences complementary to homologous amino-acid transfer ribonucleic acid molecules which serve as the translating device between polyribonucleotides and proteins. This implies that the RNA molecules have their primary origin in DNA. From the amount of DNA participating, one would infer that more than 20 complementary sequences exist per genome, a conclusion consistent with a degenerate code. The fact that complex formation occurs most readily with homologous RNA suggests that, while the language remains universal, each dictionary is uniquely identifiable with its own genome.
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