Artigo Revisado por pares

Protection from gamma-radiation insult to antioxidant defence and cellular DNA by POLY-MVA, a dietary supplement containing palladium-lipoic acid formulation

2009; Inderscience Publishers; Volume: 6; Issue: 3 Linguagem: Inglês

10.1504/ijlr.2009.028892

ISSN

1741-9190

Autores

Aditya Menon, Chirakkal V. Krishnan, Cherupally Krishnan Krishnan Nair,

Tópico(s)

biodegradable polymer synthesis and properties

Resumo

Whole-body exposure to gamma radiation was found to result in damage to cellular DNA and lowering of antioxidant levels in various tissues. Administration of POLY-MVA, a palladium-lipoic acid formulation, for seven days prior to whole body gamma radiation significantly reduced the damage to cellular DNA in bone marrow and blood leukocytes, as well as preventing the radiation-induced lowering of tissue antioxidant levels.

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