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The contribution of HIV-discordant relationships to new HIV infections in Rakai, Uganda

2011; Lippincott Williams & Wilkins; Volume: 25; Issue: 6 Linguagem: Inglês

10.1097/qad.0b013e3283448790

1473-5571

Ron Gray, Victor Ssempiija, James D Shelton, David Serwadda, Fred Nalugoda, Joseph Kagaayi, Godfrey Kigozi, Maria J. Wawer,

Adolescent Sexual and Reproductive Health

We determined HIV infections in the Rakai cohort before (82/9434) and after (131/13082) the availability of antiretroviral therapy (ART). The proportions of total HIV infections pre-ART and post-ART were 18.3% and 13.7%, respectively, among identifiable HIV-discordant couples, 23.2% and 26.0%, respectively, in concordant HIV-negative couples, 29.3% and 17.6% in married persons with unknown partner status, and 29.3% and 42.7% in the unmarried. Voluntary counseling and testing targeting discordant couples is unlikely to have a substantial impact in this setting.