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Changes in Repolarization Dynamicity and the Assessment of the Arrhythmic Risk

1997; Wiley; Volume: 20; Issue: 10 Linguagem: Inglês

10.1111/j.1540-8159.1997.tb06111.x

1540-8159

Pierre Maison‐Blanche, P Coumel,

Ion channel regulation and function

At the present time, the assessment of the arrhythmic risk from surface ECG recordings is built on time‐domain and frequenct‐domain analysis of high resolution ECG acquisition together with in‐terlead variability of QT interval duration (QT dispersion). The corresponding raw ECG tracings are obtained in resting conditions. However, the dynamic aspects of the EGG signal is a rapidly evolving matter of interest. In addition to the beat‐to‐beat oscillations of the ventricular repolarization amplitude (QT ai‐ternans), there is growing evidence that the patterns of QT interval shortening with increasing heart rate are linked to suceptibility to ventricular arhythmias. In this report, we will mailnly address the association between QT dynamicity and the risk of developing torsades de pointes.