Chirally templated boronic acid Mannich reaction in the synthesis of optically active α-amino acids
2000; Royal Society of Chemistry; Issue: 17 Linguagem: Inglês
10.1039/b003067h
ISSN2050-8263
AutoresGordon S. Currie, Michael G. B. Drew, Laurence M. Harwood, David Hughes, Richard Luke, Richard Vickers,
Tópico(s)Chemical Synthesis and Analysis
ResumoAdducts from diastereoselective Mannich-type reactions of aldehydes, 2-furylboronic acid and the chiral amine template (S)-5-phenylmorpholin-2-one, have been used in the synthesis of a series of enantiomerically pure D-α-amino acids.
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