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Experimental model of double wounds on the rats back , in order to study the skin cicatrization process on rat treated with cellulose coat

2003; Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia; Volume: 18; Issue: spe Linguagem: Inglês

10.1590/s0102-86502003001100010

1678-2674

Lecy Marcondes Cabral, Lydia Masako Ferreira, Manuel de Jesus Simões, Oswaldo Alves Mora,

Bee Products Chemical Analysis

To the present study were used males rats (Rattus Norvegicus, var. Albinus, Rodentia Mammalia) EPM-1 Wistar, which came from Biotério Central da UNIFESP-EPM. Each animal was submitted to two wound of circular shape, made with a "punch", with superficial cuts of 2 cm diameter; located on medium line of dorsal region. In the present study, one wound was re-covered with the cellulose coat and the other serves as a control. This experimental form, makes it possible to us realize different studies such as macroscopic aspects of the wounds as well morphometric and morphological parameters analysis.