Antitumor Enzyme: Polyethylene Glycol–modified Asparaginase
1990; Wiley; Volume: 613; Issue: 1 Linguagem: Inglês
10.1111/j.1749-6632.1990.tb18151.x
ISSN1749-6632
AutoresHiroshi Wada, Ikuo Imamura, Makoto Sako, Sayaka Katagiri, S Tarui, Hitoshi Nishimura, Y. Inada,
Tópico(s)Diverse Education Studies and Reforms
ResumoAnnals of the New York Academy of SciencesVolume 613, Issue 1 p. 95-108 Antitumor Enzyme: Polyethylene Glycol–modified Asparaginase H. WADA, H. WADA Department of Pharmacology II Osaka University School of Medicine 3-57 Nakanoshima 4-chome, Kitaku Osaka 530, JapanSearch for more papers by this authorI. IMAMURA, I. IMAMURA Department of Pharmacology II Osaka University School of Medicine 3-57 Nakanoshima 4-chome, Kitaku Osaka 530, JapanSearch for more papers by this authorM. SAKO, M. SAKO Department of Pediatrics I Medical Center of Pediatric Health of Osaka City Osaka 537, JapanSearch for more papers by this authorS. KATAGIRI, S. KATAGIRI Department of Medicine II Osaka University School of Medicine Osaka 530, JapanSearch for more papers by this authorS. TARUI, S. TARUI Department of Medicine II Osaka University School of Medicine Osaka 530, JapanSearch for more papers by this authorH. NISHIMURA, H. NISHIMURA dDepartment of Pathology School of Medicine Juntendo University Tokyo 113, JapanSearch for more papers by this authorY. INADA, Y. INADA eDepartment of Materials Science and Technology Toin University of Yokohama Yokohama 227, JapanSearch for more papers by this author H. WADA, H. WADA Department of Pharmacology II Osaka University School of Medicine 3-57 Nakanoshima 4-chome, Kitaku Osaka 530, JapanSearch for more papers by this authorI. IMAMURA, I. IMAMURA Department of Pharmacology II Osaka University School of Medicine 3-57 Nakanoshima 4-chome, Kitaku Osaka 530, JapanSearch for more papers by this authorM. SAKO, M. SAKO Department of Pediatrics I Medical Center of Pediatric Health of Osaka City Osaka 537, JapanSearch for more papers by this authorS. KATAGIRI, S. KATAGIRI Department of Medicine II Osaka University School of Medicine Osaka 530, JapanSearch for more papers by this authorS. TARUI, S. TARUI Department of Medicine II Osaka University School of Medicine Osaka 530, JapanSearch for more papers by this authorH. NISHIMURA, H. NISHIMURA dDepartment of Pathology School of Medicine Juntendo University Tokyo 113, JapanSearch for more papers by this authorY. INADA, Y. INADA eDepartment of Materials Science and Technology Toin University of Yokohama Yokohama 227, JapanSearch for more papers by this author First published: December 1990 https://doi.org/10.1111/j.1749-6632.1990.tb18151.xCitations: 45AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Maita, T., K. Morokuma & G. Matsuda. 1974. Amino acid sequence of l-asparaginase from Escherichia coli. J. Biochem. 76: 1351–1354. 2 Clarkson, B., I. Krakoff, J. Burchenal, D. Karnofsky, R. Golbey, M. Dowling, H. Oettgen & A. Lipton. 1970. Clinical results of treatment with E. coli l-asparaginase in adults with leukemia, lymphoma, and solid tumors. Cancer 25: 279–305. 3 Ertel, I. J., M. E. Nesbit, D. Hammond, J. Weiner & H. Sather. 1979. Effective dose of l-asparaginase for induction of remission in previously treated children with acute lymphocytic leukemia: a report from a children's cancer study group. Cancer Res. 39: 3893–3896. 4 Capizzi, R. L. 1981. Asparaginase-methotrexate in combination chemotherapy: schedule-dependent differential effects on normal versus neoplastic cells. Cancer Treatment Rep. 65(suppl. 4): 115–121. 5 Ashihara, Y., T. Kono, S. Yamazaki & Y. Inada. 1978. Modification of E. coli l-asparaginase with polyethylene glycol: disappearance of binding ability to anti-asparaginase serum. Biochem. Biophys. Res. Commun. 83: 385–391. 6 Park, Y. K., A. Abuchowski, S. Davis & F. Davis. 1981. Pharmacology of Escherichia coli l-asparaginase polyethylene glycol adduct. Anticancer Res. 1: 373–376. 7 Carpenter, C. P., M. D. Woodside, E. R. Kinkead, J. M. King & L. J. Sullivan. 1971. Response of dogs to repeated intravenous injection of polyethylene glycol 4000 with notes on excretion and sensitization. Toxicol. Appl. Pharmacol. 18: 35–40. 8 Matsushima, A., H. Nishimura, Y. Ashihara, Y. Yokota & Y. Inada. 1980. Modification of E. coli asparaginase with 2,4-bis(O-methoxypolyethylene glycol)-6-chloro-s-triazine (activated PEG2): disappearance of binding ability towards anti-serum and retention of enzymic activity. Chem. Lett. 7: 773–776. 9 Nishimura, H., A. Matsushima & Y. Inada. 1981. 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Increased antitumor activity of Escherichia coli l-asparaginase by modification with monomethoxypolyethylene glycol. Jpn. J. Cancer Res. (Gann) 73: 470–474. 14 Kawamura, K., T. Igarashi, T. Fujii, Y. Kamisaki, H. Wada & S. Kishimoto. 1985. Immune responses to polyethylene glycol modified l-asparaginase in mice. Int. Arch. Allergy Appl. Immunol. 76: 324–330. 15 Inada, Y., A. Matsushima, Y. Saito, T. Yoshimoto, H. Nishimura & H. Wada. 1989. Synthetic polymer-protein hybrids: modification of l-asparaginase with polyethylene glycol. In Multiphase Biomedical Materials. T. Tsuruta & A. Nakajima, Eds.: 153–166. Intern. Sci. Pub. The Netherlands . 16 Luk, G. D., W. P. Vaughan, P. J. Burke & S. B. Baylin. 1981. Diamine oxidase as a plasma marker of rat intestinal mucosal injury and regeneration after administration of 1-β-d-arabinofuranosylcytosine. Cancer Res. 41: 2334–2337. 17 Luk, G. D., T. M. Bayless & S. B. Baylin. 1983. Plasma postheparin diamine oxidase. J. Clin. Invest. 71: 1308–1315. Citing Literature Volume613, Issue1Enzyme Engineering 10December 1990Pages 95-108 ReferencesRelatedInformation
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