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Negative inotropic effect of some H2-receptor antagonists on the isolated human atria

1983; Birkhäuser; Volume: 39; Issue: 11 Linguagem: Inglês

10.1007/bf01990372

0014-4754

Gabriella Coruzzi, E. Poli, F Fesani, D Medici, G. Bertaccini,

Asthma and respiratory diseases

H2-Receptor antagonists were found to possess in various degrees a negative inotropic effect on human atria in vitro. This effect seemed to be independent of H2-receptor blockade and, at least in the case of oxmetidine, seemed to involve calcium ion transport and/or utilization.