One- and Two-Photon Turn-on Fluorescent Probe for Cysteine and Homocysteine with Large Emission Shift
2009; American Chemical Society; Volume: 11; Issue: 6 Linguagem: Inglês
10.1021/ol802979n
ISSN1523-7060
AutoresXuanjun Zhang, Xinsheng Ren, Qing‐Hua Xu, Kian Ping Loh, Zhi‐Kuan Chen,
Tópico(s)Nanoplatforms for cancer theranostics
ResumoA novel dendritic chromophore with efficient intramolecular charge transfer (ICT) and strong two-photon absorption (TPA) was designed as a turn-on fluorescent probe for cysteine (Cys) and homocysteine (Hcy). The probe exhibited greatly enhanced fluorescence intensity as well as a very large emission peak shift (165 nm) upon addition of Cys/Hcy due to ICT switch off. The sensing process was also monitored by two-photon excited fluorescence (TPEF).
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