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Lichen Planus and Discoid Lupus Erythematosus

1978; American Medical Association; Volume: 114; Issue: 7 Linguagem: Inglês

10.1001/archderm.1978.01640190027009

1538-3652

Thomas H. Jamison,

Coagulation, Bradykinin, Polyphosphates, and Angioedema

• A patient with the discoid lupus erythematosus and lichen planus overlap syndrome had profound depression of serum C4 concentration associated with substantial mixed cryoblobulinemia. A family study failed to disclose evidence of a familial hypocomplementemia, cryoglobulinemia, or a dermatologic condition. Immunoglobulin, but no complement, was detected at the site of the skin abnormality. This case illustrates an immune-complex disorder with a mixed cryoglobulinemia that is related to immunoglobulin deposition in the skin. ( Arch Dermatol 114:1039-1042, 1978)