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Rimorphin, a unique, naturally occurring [Leu]enkephalin-containing peptide found in association with dynorphin and alpha-neo-endorphin.

1982; National Academy of Sciences; Volume: 79; Issue: 21 Linguagem: Inglês

10.1073/pnas.79.21.6480

ISSN

1091-6490

Autores

D L Kilpatrick, Agneta Wahlström, H W Lahm, Russell Blacher, Sidney Udenfriend,

Tópico(s)

Neuroendocrine regulation and behavior

Resumo

The tridecapeptide NH2-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-COOH has been purified from extracts of bovine posterior pituitary glands. This unique peptide, which has been given the name "rimorphin," is a major [Leu]enkephalin-containing peptide in all tissues examined that contain dynorphin and alpha-neo-endorphin. However, except for the initial hexapeptide sequence, it is structurally unrelated to the other two peptides.

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