Artigo Revisado por pares

Incidence and Early Course of Retlnonathy of Prematurity

1991; Elsevier BV; Volume: 98; Issue: 11 Linguagem: Inglês

10.1016/s0161-6420(91)32074-8

ISSN

1549-4713

Autores

Earl A. Palmer, John T. Flynn, Robert J. Hardy, Dale L. Phelps, Cynthia L. Phillips, David B. Schaffer, Betty Tung, Frederick J. Elsas, Jan M. Botsford, Karen W. Braune, George Cassady, John A. Jones, James A. Kimble, Lanning B. Kline, Douglas Witherspoon, Malinda Young, Alan M. Roth, Byron H. Demorest, Roberta Erickson, W. S. Gilbert, Georgia Antonakou Chrousos, David S. Friendly, Mohammad Jaafar, Marshall P. Keys, Martin P. Kolsky, P. Mercer, Donna O’Neill, John F. O’Neill, Edward S. Parelhoff, Ed Perraut, A. Raymond Pilkerton, David Plotsky, John T. Flynn, John G. Clarkson, Gabrielle Lopez, Marilyn T. Miller, Rama Bhat, Steven B. Cohen, Cathleen M. Cronin, Mark J. Daily, Donald A. Gagliano, Richard Gieser, Betty Anne Haldi, Kristine M. McCulloch, David Mittelman, Tonse N.K. Raju, D Sheftel, Kathleen Skuran, Daniel B. Sobel, P Squires, Charles M. Vygantas, Forrest D. Ellis, Stephen D. Archer, Eugene M. Helveston, Ken Julian, Gayle Reed, Richard L. Schreiner, Charles C. Barr, David N. Adamkin, Craig Douglas, Gregory K. Whittington, Shirley A. Wilkerson, Robert Gordon, Carolyn Bushaw, W. M. DeVoe, James G. Diamond, William L. Gill, Donald R. May, Jane Reynolds, Thomas G. Storch, Serge de Bustros, Alethia Alford, Janet E Graeber, Michael X. Repka, Michael T. Trese, John D. Baker, Ghaleb F. Hatem, Patricia Manatrey, Doreen Medalis, Robert C. Ramsay, C. Gail Summers, J. Douglas Cameron, K.W. Chisholm, Rebecca Heikenen, Donna K. Irlbeck, Alvina M. Janda, Leslie A. Kopietz, Robin Kriedeman, Jane Dunn Lavoie, Molly Maxwell, Ted R. Pier, William P. Rodman, Patty Witt, Amy Woody, Dale L. Phelps, Paul F. Torrisi, Thaddeus Zak, Kathy Cohen, Rajesh J. Dave, Ernest Guillet, David O. Hakanson, Robert Hampton, Walter W. Merriam, Henry S Metz, Ellen Pronobis, Richard Simon, Robert E. Vanderlinde, Nancy Wood, Donald N Zehl, Edward Buckley, Malcolm M. Anderson, Grace Valentine, Susie Wong, Miles J. Burke, Judith Johnson, Gary L. Rogers, Don L. Bremer, Leandro Cordero, Rae R. Fellows, Nancy B. Hansen, Richard E. McClead, Earl A. Palmer, Arthur A. Aaby, Raul C. Banagale, Gerda I. Benda, Nancy D. Binder, William J. Brown, Joseph Gilhooly, Shawn S. Goodman, Robert K. Huston, Susan B. LaFrance, Patrick K. Lewallen, John V. McDonald, David L. Murphy, John W. Reynolds, Joseph E. Robertson, Andrea Cibis Tongue, David B. Schaffer, Frank W. Bowen, Maria Delivoria‐Papadopoulos, Hemant Desai, Gary R. Diamond, Joan M. Giannetta, Michael A. Naidoff, George J. Peckham, Jeanette R. Pleasure, Rachael Porat, Graham E. Quinn, Albert W. Biglan, David R. Brown, Bernard H. Doft, Andrew W. Eller, Louis A. Lobes, Richard Saunders, Linda M. Christmann, Tom L. Austin, L. M. Berkeley, James Ferguson, Wilson G. McWilliams, Karen W. Miller, Sharada Pai, Vytautas A. Pakalnis, Dilip M. Purohit, Stephen S. Feman, Robert B. Cotton, James H. Elliott, Amy B Law, Steven Steele, Rand Spencer, Priscilla M. Berry, Gary E. Fish, Dwain Fuller, William L. Hutton, Joel Lefer, Jean R. Manning, George E. Sanborn, William B. Snyder, David R. Stager, W. A. J. van Heuven, Marilyn Escobedo, Maria G. Montez, James W. Speights, Jane D. Kivlin, Susan Bracken, John A. Carver, Jack L. Dolcourt, Robert O. Hoffman, Michael Teske, Angelia Williams,

Tópico(s)

Neonatal Health and Biochemistry

Resumo

In the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity (ROP), 4099 infants weighing less than 1251 g at birth underwent sequential ophthalmic examinations, beginning at age 4 to 6 weeks, to monitor the incidence and course of ROP. Overall, 65.8% of the infants developed ROP to some degree; 81.6% for infants of less than 1000 g birth weight. As expected, ROP incidence and severity were higher in lower birth weight and gestational age categories. Black infants appeared less susceptible to ROP, of all severity categories, than nonblack infants. The timing of retinal vascular events correlated more closely with postconceptional age than with postnatal age, implicating the level of maturity more than postnatal environmental influences in governing the timing of these vascular events. These results include the current incidence of various severity stages of ROP found in the United States and provide new. insight into the development of ROP.

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