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Pneumocystis carinii infection in non-AIDS patients

1999; Lippincott Williams & Wilkins; Volume: 12; Issue: 4 Linguagem: Inglês

10.1097/00001432-199908000-00011

1473-6527

Robert F. Miller,

Drug-Induced Adverse Reactions

Infection with the opportunist fungus Pneumocystis carinii remains a significant cause of morbidity and mortality in non-HIV-infected individuals immunosuppressed by a wide range of malignancies, transplantation and inflammatory conditions. Glucocorticoid use appears to be an independent risk factor for the development of Pneumocystis carinii pneumonia. Transmission from infected to susceptible patients may occur, albeit infrequently. A diagnosis of Pneumocystis carinii pneumonia may be achieved in the majority of cases by DNA detection using polymerase chain reaction on oropharyngeal mouth washes.