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Antibacterial activities of root canal sealers against selected anaerobic bacteria

1996; Elsevier BV; Volume: 22; Issue: 2 Linguagem: Inglês

10.1016/s0099-2399(96)80277-9

1878-3554

José F. Siqueira, Reginaldo Bruno Gonçalves,

Dental Radiography and Imaging

The antibacterial effects of four endodontic sealers were evaluated on six anaerobic bacteria and two facultative anaerobes commonly isolated from infected root canals. Calcium hydroxide powder mixed with saline solution was also tested. The agar diffusion test was used, and the zones of inhibition around each sealer were recorded and compared. Fill Canal, a zinc oxide-eugenol-based sealer, showed large zones of inhibition against all bacteria tested. Sealer 26, an epoxy resin containing calcium hydroxide, was inhibitory to most of the strains, but it was not effective against Porphyromonas endodontalis and Porphyromonas gingivalis. Next in order was calcium hydroxide followed by Sealapex, both with low activity. Apexit showed no antibacterial activity. Difficulties in interpreting the results of agar diffusion tests are recognized. The antibacterial effects of four endodontic sealers were evaluated on six anaerobic bacteria and two facultative anaerobes commonly isolated from infected root canals. Calcium hydroxide powder mixed with saline solution was also tested. The agar diffusion test was used, and the zones of inhibition around each sealer were recorded and compared. Fill Canal, a zinc oxide-eugenol-based sealer, showed large zones of inhibition against all bacteria tested. Sealer 26, an epoxy resin containing calcium hydroxide, was inhibitory to most of the strains, but it was not effective against Porphyromonas endodontalis and Porphyromonas gingivalis. Next in order was calcium hydroxide followed by Sealapex, both with low activity. Apexit showed no antibacterial activity. Difficulties in interpreting the results of agar diffusion tests are recognized.