Artigo Revisado por pares

The Relationship Between Humoral and Cell‐Mediated Immunity

1972; Wiley; Volume: 13; Issue: 1 Linguagem: Inglês

10.1111/j.1600-065x.1972.tb00059.x

ISSN

1600-065X

Autores

Christopher R. Parish,

Tópico(s)

Antimicrobial Peptides and Activities

Resumo

Immunological ReviewsVolume 13, Issue 1 p. 35-66 The Relationship Between Humoral and Cell-Mediated Immunity C. R. Parish, C. R. Parish Department of Microbiology, John Curtin School of Medical Research, Australian National University, Canberra, A.C.T., 2600, Australia.Search for more papers by this author C. R. Parish, C. R. Parish Department of Microbiology, John Curtin School of Medical Research, Australian National University, Canberra, A.C.T., 2600, Australia.Search for more papers by this author First published: December 1972 https://doi.org/10.1111/j.1600-065X.1972.tb00059.xCitations: 74AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Ada, G. L. & Parish, C. R. (1968) Low zone tolerance to bacterial flagellin in adult rats. A possible role for antigen localized in lymphoid follicles. Proc. nat. Acad. Set (Wash.) 61, 556. 10.1073/pnas.61.2.556 CASPubMedWeb of Science®Google Scholar Asherson, G. L. & Stone, S. H. (1965) Selective and specific inhibition of 24-hour skin reactions in the guinea pig. I. Immune deviation: description of the phenomenon and the effect of splenectomy. Immunology 9, 205. CASPubMedWeb of Science®Google Scholar Austin, C. M. & Nossal, G. J. V. (1966) Mechanism of induction of immunological tolerance. III. Cross-tolerance amongst fiagellar antigens. Aust. J. exp. Biol. med. Sci. 44, 341. 10.1038/icb.1966.33 Web of Science®Google Scholar Axelrad, M. A. (1968) Suppression of delayed hypersensitivity by antigen and antibody. Is a common precursor cell responsible for both delayed hypersensitivily and antibody formation Immunology 15, 159. PubMedWeb of Science®Google Scholar Basten, A., Miller, J. F. A. P., Sprent, J. & Pye, J. (1972) A receptor for antibody on B lymphocytes. 1. Method of detection and functional significance. J. exp. Med. 135, 610. 10.1084/jem.135.3.610 CASPubMedWeb of Science®Google Scholar Basten, A., Warner, N. L. & Mandel, T. (1972) A receptor for antibody on B lymphocytes. II. Immunochemical and electron microscopy characteristics. J. exp. Med. 135. 627. 10.1084/jem.135.3.627 CASPubMedWeb of Science®Google Scholar Battisto, J. R. & Miller, J. (1962) Immunological unresponsiveness produced in adult guinea pigs by parenteral introduction of minute quantities of hapten or protein antigen. Proc. Soc. exp. Biol. (N.Y.) 111, 111. 10.3181/00379727-111-27717 CASPubMedWeb of Science®Google Scholar Bauminger, S. & Sela, M. (1969) Specificity of immunological tolerance to synthetic polypeptides. Israel J. med. Sci. 5, 177. CASWeb of Science®Google Scholar Benacerraf, B. & Gell, P. G. H. (1959) Studies on hypersensitivity. I. Delayed and arthus-type skin reactivity to protein conjugates in guinea pigs. Immunology 2, 53. CASPubMedWeb of Science®Google Scholar Benacerraf, B., Paul, W. E. & Green, I. (1970) Hapten-carrier relationships. Ann. N.Y. Acad. Sci. 169, 93. 10.1111/j.1749-6632.1970.tb55973.x CASPubMedWeb of Science®Google Scholar Bianco, C., Patrick, R. & Nussenzweig, V. (1970) A population of lymphocytes bearing a membrane receptor for antigen-antibody-complement complexes. I. Characterization and separation. J. exp. Med. 132, 702. 10.1084/jem.132.4.702 CASPubMedWeb of Science®Google Scholar Blanden, R. V. (1971) Mechanisms of recovery from a generalized viral infection; mousepox. III. Regression of infectious foci. J. exp. Med. 133, 1090. 10.1084/jem.133.5.1090 PubMedWeb of Science®Google Scholar Bloom, B. R. (1971) In vitro approaches to the mechanism of cell-mediated immune reactions. Advanc. Immunol. 13, 101. 10.1016/S0065-2776(08)60184-4 CASPubMedGoogle Scholar Boak, J. L., Mitchison, N. A. & Pattison, P. H. (1971) The carrier effect in the secondary response to hapten-protein conjugates. III. The anatomical distribution of helper cells and antibody-forming-cell-precursors. Europ. J. Immunol. 1, 63. 10.1002/eji.1830010202 PubMedGoogle Scholar Borel, Y., Fauconnet, M. & Miescher, P. A. (1966) Selective suppression of delayed hypersensitivity by the induction of immunological tolerance. J. exp. Med. 123, 585. 10.1084/jem.123.4.585 CASPubMedWeb of Science®Google Scholar Bumet, F. M. (1959) The Clonal Selection Theory of Acquired Immunity. Cambridge University Press, Cambridge , England . Google Scholar Cerottini, J. C., McConahey, P. J. & Dixon, F. J. (1969) The immunosuppressive effect of passively administered antibody IgG fragments. J. Immunol. 102, 1008. CASPubMedWeb of Science®Google Scholar Claman, H. N, & Chaperon, E. A. (1969) Immunologic complementation between thymus and marrow cells - A model for the two-cell theory of immunocompetence. Transplant. Rev. 1, 92. 10.1111/j.1600-065X.1969.tb00137.x CASPubMedGoogle Scholar Cooper, M. G. (1972) Delayed-type hypersensitivity in the mouse. II. Transfer by thymus-derived (T) cells. Scand. J. Immunol. In press. 10.1111/j.1365-3083.1972.tb01816.x PubMedGoogle Scholar Crowle, A.J. & Hu, C. C. (1965) Inhibition of the development of delayed hypersensitivity by treatment with antiserum. J. Immunol. 94, 555. PubMedWeb of Science®Google Scholar Crowle, A. J. & Hu, C. C. (1966) Split tolerance affecting delayed hypersensitivity and induced in mice by preimmunization with protein antigens in solution. Clin. exp. Immunol. 1, 323. CASPubMedGoogle Scholar Crowle, A.J. & Hu, C. C. (1968) Specificity of inhibition by antiserum of the development of immediate and delayed hypersensitivities in mice. Proc. Soc. exp. Biol. (N.Y.) 127, 190. 10.3181/00379727-127-32653 PubMedWeb of Science®Google Scholar Crowle, A.J. & Hu, C. C. (1969) Adoptive transfer of immunologic tolerance into normal mice. J. Immunol. 103, 1242. CASPubMedWeb of Science®Google Scholar Cunningham, A. J. & Sercarz, E. E. (1971) The asynchronous development of immunological memory in helper (T) and precursor (B) cell lines. Europ. J. Immunol. 1, 413. 10.1002/eji.1830010602 PubMedWeb of Science®Google Scholar Davies, A. J. S. (1969) The thymus and the cellular basis of immunity. Transplant. Rev. 1, 43. 10.1111/j.1600-065X.1969.tb00136.x CASPubMedGoogle Scholar Dresser, D. W. (1962a) Specific inhibition of antibody production. I. Protein-overloading paralysis. Immunology 5, 161. CASPubMedWeb of Science®Google Scholar Dresser, D. W. (1962b) Specific inhibition of antibody production. II. Paralysis induced in adult mice by small quantities of protein antigen. Immunology 5, 378. CASPubMedWeb of Science®Google Scholar Dresser, D. W. & Mitchison, N. A. (1968) The mechanism of immunological paralysis. Advanc. Immunol. 6, 253. Google Scholar Dukor, P., Bianco, C. & Nussenzweig, V. (1970) Tissue localization of lymphocytes bearing a membrane receptor for antigen-antibody-complement complexes. Proc. nat. Acad. Sci. (Wash.) 67, 991. 10.1073/pnas.67.2.991 CASPubMedWeb of Science®Google Scholar Dvorak, H. F., Biliote, J. B., McCarthy, J. S. & Flax, M. H. (1965) Immunological unresponsiveness in the adult guinea pig. I. Suppression of delayed hypersensitivity and antibody formation by protein antigens. J. Immunol. 94, 966. PubMedWeb of Science®Google Scholar Falkoff, R. & Kettman, J. (1972) Differential stimulation of precursor cells and carrier-specific thymus-derived cell activity in the in vivo response to heterologous erythrocytes in mice. J. Immunol. 108, 54. CASPubMedWeb of Science®Google Scholar Feldmann, M. & Diener, E. (1970) Antibody-mediated suppression of the immune response in vitro. I. Evidence for a central effect. J. exp. Med. 131, 247. 10.1084/jem.131.2.247 CASPubMedWeb of Science®Google Scholar Feldmann, M. & Basten, A. (1972) Specific collaboration between T and B lymphocytes across a cell impermeable membrane in vitro. Nature New Biol. 237, 13. 10.1038/newbio237013a0 CASPubMedWeb of Science®Google Scholar Fidler, J. M., McDaniel, E. M. & Golub, E. S. (1972) Regulation of the immune response. III. Effect of the 'accelerated' response on hapten-carrier responses. Cell. Immunol. 4, 29. 10.1016/0008-8749(72)90003-2 CASPubMedWeb of Science®Google Scholar Fishman, M. (1969) Induction of antibodies in vitro. Ann. Rev. Microbiol. 23, 199. 10.1146/annurev.mi.23.100169.001215 CASPubMedWeb of Science®Google Scholar Gell, P. G. H. & Benacerraf, B. (1959) Studies on hypersensitivity. II. Delayed hyper-sensitivity to denatured proteins in guinea pigs. Immunology 2, 64. CASPubMedWeb of Science®Google Scholar Gell, P. G. H. & Benacerraf, B. (1961) Delayed hypersensitivity to simple protein antigens. Advanc. Immunol. 1, 319. 10.1016/S0065-2776(08)60768-3 CASWeb of Science®Google Scholar Hartmann, K., Dutton, R. W., McCarthy, M. M. & Mishell, R. I. (1970) Cell components in the immune response. II. Cell attachment separation of immune cells. Cell Immunol. 1, 182. 10.1016/0008-8749(70)90005-5 PubMedGoogle Scholar Hellström, K. E. & Hellstrom, I. (1970) Immunological enhancement as studied by cell culture techniques. Ann. Rev. Microbiol. 24, 373. 10.1146/annurev.mi.24.100170.002105 PubMedWeb of Science®Google Scholar Hellström, I., Hellstrom, K. E. & Allison, A. C. (1971) Neonatally induced allograft tolerance may be mediated by serum-borne factors. Nature (Lond.) 230, 49. 10.1038/230049a0 PubMedWeb of Science®Google Scholar Henry, C. & Jerne, N. K. (1968) Competition of 19S and 7S antigen receptors in the regulation of the primary immune response. J. exp. Med. 128, 133. 10.1084/jem.128.1.133 CASPubMedWeb of Science®Google Scholar Hoffmann, M. & Kappler, J. W. (1972) The antigen specificity of thymus-derived helper cells. J. Immunol. 108, 261. PubMedWeb of Science®Google Scholar Ichiki, A. T. & Parish, C. R. (1972a) Cleavage of bacterial flagellin with proteolytic enzymes. I. Physicochemical and antigenic properties of the tryptic and peptic peptides. Immunochemistry 9, 153. 10.1016/0019-2791(72)90036-5 CASPubMedWeb of Science®Google Scholar Ichiki, A. T. & Parish, C. R. (1972b) Cleavage of bacterial flagellin with proteolytic enzymes. II. Induction of enhanced delayed-type hypersensitivity to flagellin by peptic fragments of the protein. Cell. Immunol. In press. 10.1016/0008-8749(72)90030-5 Web of Science®Google Scholar Ivanyi, J. (1970) Cytophilic antibodies in passive antibody induced immune suppression or enhancement. Nature (Lond.) 226, 550. 10.1038/226550b0 CASPubMedWeb of Science®Google Scholar Janicki, B. W., Scbechter, G. P. & Schultz, K. E. (1970) Cellular reactivity to tuberculin in immune and serologically-unresponsive guinea pigs. J. Immunol. 105, 527. PubMedWeb of Science®Google Scholar Jones, V. E. & Leskowitz, S. (1965) Role of the carrier in development of delayed sensitivity to the azophenyl-arsonate group. Nature (Lond.) 207, 596. 10.1038/207596a0 CASPubMedWeb of Science®Google Scholar Kaliss, N. (1958) Immunological enhancement of tumour homografts in mice. Cancer Res. 18, 992. PubMedWeb of Science®Google Scholar Kappler, J. W., Hoffman, M. & Dutton, R. W. (1971) Regulation of the immune response. I. Differential effect of passively administered antibody on the thymus-derived and bone marrow-derived lymphocytes. J. exp. Med. 134, 577. 10.1084/jem.134.3.577 CASPubMedWeb of Science®Google Scholar Lang, W., Nase, S. & Rajewsky, K. (1969) Inhibition of the immune response in vitro to sheep red blood cells by passive antibody. Nature (Lond.) 223, 949. 10.1038/223949a0 CASPubMedWeb of Science®Google Scholar Lennon, V. A., Wilks, A. V. & Carnegie, P. R. (1970) Immunologic properties of the main encephalitogenic peptide from the basic protein of human myelin. J. Immunol. 105, 1223. 10.4049/jimmunol.105.5.1223 CASPubMedWeb of Science®Google Scholar Levine, B. B. (1965) Studies on delayed hypersensitivity. I. Inferences on the comparative binding affinities of antibodies mediating delayed and immediate hypersensitivity reactions in the guinea pig. J. exp. Med. 121, 873. 10.1084/jem.121.6.873 CASPubMedWeb of Science®Google Scholar Liew, F. Y. & Parish, C. R. (1972a) Regulation of the immune response by antibody. I. Suppression of antibody formation and concomitant enhancement of cell-mediated immunity by passive antibody. Cell. Immunol. 4, 66. 10.1016/0008-8749(72)90006-8 CASPubMedWeb of Science®Google Scholar Liew, F. Y. & Parish, C. R. (1972b) Regulation of the immune response by antibody. II. The effect of different classes of passive antibody on bumoral and cell-mediated immunity. Cell. Immunol. In press. Google Scholar Liew, F. Y. & Parish, C. R. (1972c) Regulation of the immune response by antibody. III. The effect of macrophage cytophilic antibody on humoral and cell-mediated immunity. Celt. Immunol. In press. Google Scholar Loewi, G. E., Holborow, E. J. & Temple, A. (1966) Inhibition of delayed hypersensitivity by preimmunization without complete adjuvant, Immunology 10, 339. CASPubMedWeb of Science®Google Scholar Mackaness, G. B. & Hill, W. C. (1969) The effect of anti-lymphocyte globulin on cell-mediated resistance to infection. J. exp. Med. 129, 993. 10.1084/jem.129.5.993 CASPubMedWeb of Science®Google Scholar McCullagh, P. J. (1970) The abrogation of sheep erythrocyte tolerance in rats by means of the transfer of allogeneic lymphocytes. J. exp. Med. 132, 916. 10.1084/jem.132.5.916 PubMedWeb of Science®Google Scholar Miller, J. F. A. P. & Mitchell, G. F. (1969) Thymus and antigen-reactive cells. Transplant. Rev. 1, 3. 10.1111/j.1600-065X.1969.tb00135.x CASPubMedGoogle Scholar Miller, J. F. A. P., Basten, A., Sprent, J. & Cheers, C. (1971) Interaction between lymphocytes in immune responses. Cell. Immunol. 2, 469. 10.1016/0008-8749(71)90057-8 CASPubMedWeb of Science®Google Scholar Mitchison, N. A. (1964) Induction of immunological paralysis in two zones of dosage. Proc. roy. Soc. B 161, 275. 10.1098/rspb.1964.0093 CASPubMedWeb of Science®Google Scholar Mitchison, N. A. (1971a) The carrier effect in the secondary response to hapten-protein conjugates. I. Measurement of the effect with transferred cells and objections to the local environment hypothesis. Europ. J. Immunol. 1, 10. 10.1002/eji.1830010103 CASPubMedGoogle Scholar Mitchison, N. A. (1971b) The carrier effect in the secondary response to hapten-protein conjugates. II. Cellular cooperation. Europ. J. Immunol. I, 18. 10.1002/eji.1830010104 CASGoogle Scholar Mitchison, N. A. (1971c) The carrier effect in the secondary response to haplen-protein conjugates. V. Use of antilymphocyte serum to deplete animals of helper cells. Europ. J. Immunol. 1, 68. 10.1002/eji.1830010204 CASPubMedGoogle Scholar Möller, G. (1964) Antibody-induced depression of the immune response: a study of the mechanism in various immunological systems. Transplantation 2, 405. 10.1097/00007890-196405000-00010 CASPubMedWeb of Science®Google Scholar Möller, G. & Wigzell, H. (1965) Antibody synthesis at the cellular level. Antibody-induced suppression of 19S and 7S antibody response. J. exp. Med. 121, 969. 10.1084/jem.121.6.969 CASPubMedWeb of Science®Google Scholar Möller, G. & Möller, E. (1966) In: Antibodies to Biologically Active Molecules, ed. B. Cinader, pp. 349–407. Pergamon, Oxford . Google Scholar Morris, A. & Möller, G. (1968) Regulation of cellular antibody synthesis. Effect of adoptively transferred antibody-producing spleen cells on cellular antibody synthesis. J. Immunol. 101, 439. PubMedWeb of Science®Google Scholar Mosier, D. E. (1967) A requirement for two cell types for antibody formation in vitro. Science 158, 1573. 10.1126/science.158.3808.1573 PubMedGoogle Scholar Nossal, G. J. V., Ada, G. L. & Austin, C. M. (1964) Antigens in immunity. II. Immunogenic properties of flagella, polymerized flagellin and flagellin in the primary response. Aust. J. exp. Biol. med. Sci. 42, 283. 10.1038/icb.1964.30 CASPubMedWeb of Science®Google Scholar Pappenheimer, A. M. & Freund, J. (1959) Induction of delayed hypersensitivity to protein antigens. In: Cellular and Humoral Aspects of the Hypersensitive State, ed. Lawrence Sherwood, H. Cassell, London . Google Scholar Parish, C. R. (1971a) Suppression of antibody formation and concomitant enhancement of cell-mediated immunity by acetoacetylated derivatives of Salmonella flagellin. Ann. N.Y. Acad. Sci. 181, 108. 10.1111/j.1749-6632.1971.tb49818.x CASWeb of Science®Google Scholar Parish, C. R. (1971b) Immune response to chemically modified flagellin. I. Induction of antibody tolerance to flagellin by acetoacetylated derivatives of the protein. J. exp. Med. 134, 1. 10.1084/jem.134.1.1 CASPubMedWeb of Science®Google Scholar Parish, C. R. (1971c) Immune response to chemically modified flagellin. II. Evidence for a fundamental relationship between humoral and cell-mediated immunity. J. exp. Med. 134, 21. 10.1084/jem.134.1.21 CASPubMedWeb of Science®Google Scholar Parish, C. R. (1972a) Preferential induction of cell-mediated immunity by chemically modified sheep erythrocytes. Europ. J. Immunol. 2, 143. 10.1002/eji.1830020210 CASPubMedWeb of Science®Google Scholar Parish, C. R. (1972b) Immune response to chemically modified flagellin. IV. Further studies on the relationship between humoral and cell-mediated immunity. Cell. Immunol. In press. Google Scholar Parish, C. R., Wistar, R. & Ada, G. L. (1969) Cleavage of bacterial flagellin with cyanogen bromide. Antigenic properties of the protein fragments. Biochem. J. 113, 501. 10.1042/bj1130501 CASPubMedWeb of Science®Google Scholar Parish, C. R. & Liew, F. Y. (1972) Immune response to chemically modified flagellin. III. Enhanced cell-mediated immunity during high and low zone antibody tolerance to flagellin. J. exp. Med. 135, 298. 10.1084/jem.135.2.298 CASPubMedWeb of Science®Google Scholar Parish, C. R. & Stanley, P. (1972) The chemical and biological properties of bacterial flagellin following iodination and oxidation with chloramine-T. Immunochemistry. In press. 10.1016/0019-2791(72)90160-7 PubMedWeb of Science®Google Scholar Payling Wright, G. (1968) Protective immunity. In: Clinical Aspects of Immunology, ed. P.G.H. Gell & R. R. A. Coombs Blackwell, Oxford . Google Scholar Pearson, M. N. & Raffel, S. (1971) Macrophage-digested antigen as inducer of delayed hypersensitivity. J. exp. Med. 133, 494. 10.1084/jem.133.3.494 CASPubMedWeb of Science®Google Scholar Pierce, C. W. (1969) Immune responses in vitro. II. Suppression of the immune response in vitro by specific antibody. J. exp. Med. 130, 365. 10.1084/jem.130.2.365 PubMedWeb of Science®Google Scholar Raff, M. C. (1970) Role of thymus-derived lymphocytes in the secondary humoral immune response in mice. Nature (Lond.) 226, 1257. 10.1038/2261257a0 CASPubMedGoogle Scholar Rajewsky, K., Schirrmacber, V., Nase, S. & Jeme, N. K. (1969) The requirement of more than one antigenic determinant for immunogenicity. J. exp. Med. 129, 1131. 10.1084/jem.129.6.1131 CASPubMedWeb of Science®Google Scholar Rowley, D. A. & Fitch, F. W. (1964) Homeostasis of antibody formation in the adult rat. J. exp. Med. 120, 987. 10.1084/jem.120.6.987 CASPubMedWeb of Science®Google Scholar Salvin, S. B. (1958) Occurrence of delayed hypersensitivity during the development of arthus type hypersensitivity. J. exp. Med. 107, 109. 10.1084/jem.107.1.109 CASPubMedWeb of Science®Google Scholar Salvin, S. B. & Liauw, H.L. (1967) Hypersensitivity to peptide fragments. Int. Arch. Allergy 31, 366. 10.1159/000229882 CASPubMedWeb of Science®Google Scholar Schlossman, S. F. (1972) Antigen recognition: the specificity of T cells involved in the cellular immune response. Transplant. Rev. 10, 97. 10.1111/j.1600-065X.1972.tb01540.x CASPubMedGoogle Scholar Schlossman, S. F. & Levine, H. (1967) Immunochemical studies on delayed and arthus- type hypersensitivity reactions. I. The relation between antigenic determinant size and antibody-combining site size. J. Immunol. 98, 211. CASPubMedWeb of Science®Google Scholar Sell, S. & Weigle, W. O. (1959) The relationship between delayed hypersensitivity and circulating antibody induced by protein antigens in guinea pigs. J. Immunol. 83, 257. PubMedWeb of Science®Google Scholar Shellam, G. R. & Nossal, G. J. V. (1968) Mechanism of induction of immunological tolerance. IV. The effects of ultra-low doses of flagellin. Immunology 14, 273. CASPubMedWeb of Science®Google Scholar Shortman, K., Diener, E., Russell, P. & Armstrong, W. D. (1970) The role of non- lymphoid accessory cells in the immune response to different antigens. J. exp. Med. 131, 461. 10.1084/jem.131.3.461 PubMedGoogle Scholar Shortman, K. & Palmer, J. (1971) The requirement of macrophages in the in vitro immune response. Cell. Immunol. 2, 399. 10.1016/0008-8749(71)90051-7 CASPubMedWeb of Science®Google Scholar Sinclair, N. R. St. C. (1969) Regulation of the immune response. I. Reduction in ability of specific antibody to inhibit long-lasting IgG immunological priming after removal of the Fc fragment. J. exp. Med. 129, 1183. 10.1084/jem.129.6.1183 CASPubMedWeb of Science®Google Scholar Sinclair, N. R. St. C., Lees, R. K., Chan, P. L. & Khan, R. H. (1970) Regulation of the immune response. II. Further studies on differences in ability of F(ab')a and 7S antibodies to inhibit an antibody response. Immunology 19, 105. PubMedWeb of Science®Google Scholar Snell, G.D., Winn, H.J., Stimpfling, J. H. & Parker, S. J. (1960) Depression by antibody of the immune response to homografts and its role in immunological enhancement. J. exp. Med. 112, 293. 10.1084/jem.112.2.293 CASPubMedWeb of Science®Google Scholar Stupp, Y., Borek, F. & Sela, M. (1966) Studies on the types of immune responses to synthetic antigens in guinea pigs. Immunology 11, 561. CASPubMedWeb of Science®Google Scholar Tao, T W. & Uhr, J.W. (1966) Capacity of pepsin-digested antibody to inhibit antibody formation. Nature (Lond.) 212, 208. 10.1038/212208a0 CASPubMedWeb of Science®Google Scholar Taylor, R. B. (1969) Cellular cooperation in the antibody response of mice to two serum albumins; specific function of thymus cells. Transplant. Rev. 1, 114. 10.1111/j.1600-065X.1969.tb00138.x PubMedGoogle Scholar Thompson, K., Harris, M., Benjamini, E., Mitchell, G. & Noble, M. (1972) Cellular and humoral immunity: a distinction in antigenic recognition. Nature New Biol. 238, 20. 10.1038/newbio238020a0 CASPubMedWeb of Science®Google Scholar Turk, J. L. (1967) Delayed Hypersensitivity. John Wiley and Sons, Inc., New York . Google Scholar Turk, J. L. & Bryceson, A. D. M. (1971) Immunological phenomena in leprosy and related diseases. Advanc. Immunol. 13, 209. 10.1016/S0065-2776(08)60185-6 PubMedGoogle Scholar Uhr, J.W. & Baumann, J. B. (1961) Antibody formation. I. Suppression of antibody formation by passively administered antibody. J. exp. Med. 113, 935. 10.1084/jem.113.5.935 CASPubMedWeb of Science®Google Scholar Uhr, J. W. & Möller, G. (1968) Regulatory effect of antibody on the immune response. Advanc. Immunol. 8, 81. 10.1016/S0065-2776(08)60465-4 CASPubMedGoogle Scholar Uhr, J. W. & Pappenheimer, A. N. (1958) Delayed hypersensitivity. III. Specific desensitizalion of guinea pigs sensitized to protein antigens. J. exp. Med. 108, 891. 10.1084/jem.108.6.891 CASPubMedWeb of Science®Google Scholar Voisin, G.A. (1971) Immunity and tolerance: a unified concept. Cell. Immunol. 2, 670. 10.1016/0008-8749(71)90014-1 CASPubMedWeb of Science®Google Scholar Wegmann, T. G., Hellstrom, I. & Hellstrdm, K. E. (1971) Immunological tolerance: 'Forbidden clones' allowed in tetraparental mice. Proc. nat. Acad. Sci. (Wash.) 68, 1644. 10.1073/pnas.68.7.1644 CASPubMedWeb of Science®Google Scholar Wilson, D. B. & Billingham, R. E. (1967) Lymphocytes and transplantation immunity. Advanc. Immunol. 7, 189. 10.1016/S0065-2776(08)60129-7 CASPubMedWeb of Science®Google Scholar Citing Literature Volume13, Issue1December 1972Pages 35-66 ReferencesRelatedInformation

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