Relaxant effects of benzodiazepines on isolated human umbilical arteries and veins

1993; Wiley; Volume: 13; Issue: 6 Linguagem: Inglês

10.1111/j.1474-8673.1993.tb00284.x

ISSN

1365-2680

Autores

Ana Belén Elgoyhen, Patricia S. Lorenzo, Rodolfo Pedro Rothlin, D. Spacavento, Edda Adler‐Graschinsky,

Tópico(s)

Neuroscience of respiration and sleep

Resumo

Journal of Autonomic PharmacologyVolume 13, Issue 6 p. 373-379 Relaxant effects of benzodiazepines on isolated human umbilical arteries and veins A. B. Elgoyhen, A. B. Elgoyhen Institute de Investigaciones Farmacológicas, CONICET, Junin 956, Buenos Aires 1113, ArgentinaSearch for more papers by this authorP. S. Lorenzo, P. S. Lorenzo Institute de Investigaciones Farmacológicas, CONICET, Junin 956, Buenos Aires 1113, ArgentinaSearch for more papers by this authorR. P. Rothlin, R. P. Rothlin Departamento de Farmacologia y Toxicologia, Facultad de Medicina, UBA, Paraguay 2155, Buenos Aires 1121, ArgentinaSearch for more papers by this authorD. Spacavento, D. Spacavento Departamento de Farmacologia y Toxicologia, Facultad de Medicina, UBA, Paraguay 2155, Buenos Aires 1121, ArgentinaSearch for more papers by this authorE. Adler-Graschinsky, Corresponding Author E. Adler-Graschinsky Institute de Investigaciones Farmacológicas, CONICET, Junin 956, Buenos Aires 1113, ArgentinaDr E. Adler-Graschinsky.Search for more papers by this author A. B. Elgoyhen, A. B. Elgoyhen Institute de Investigaciones Farmacológicas, CONICET, Junin 956, Buenos Aires 1113, ArgentinaSearch for more papers by this authorP. S. Lorenzo, P. S. Lorenzo Institute de Investigaciones Farmacológicas, CONICET, Junin 956, Buenos Aires 1113, ArgentinaSearch for more papers by this authorR. P. Rothlin, R. P. Rothlin Departamento de Farmacologia y Toxicologia, Facultad de Medicina, UBA, Paraguay 2155, Buenos Aires 1121, ArgentinaSearch for more papers by this authorD. Spacavento, D. Spacavento Departamento de Farmacologia y Toxicologia, Facultad de Medicina, UBA, Paraguay 2155, Buenos Aires 1121, ArgentinaSearch for more papers by this authorE. Adler-Graschinsky, Corresponding Author E. Adler-Graschinsky Institute de Investigaciones Farmacológicas, CONICET, Junin 956, Buenos Aires 1113, ArgentinaDr E. Adler-Graschinsky.Search for more papers by this author First published: December 1993 https://doi.org/10.1111/j.1474-8673.1993.tb00284.xCitations: 7AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References Antunez, P. B., Spaccavento, D., Zieher, L. M. and Rothlin, R. P. (1990). Función del endotelio en la acción vasoconstrictora de la histamina en vena umbilical humana. Medicina, 50, 77P. Chaudhuri, G., Buga, G. M., Gold, M. E., Wood, K. S. and; Ignarro, L. J. (1991). Characterization and actions of human umbilical endothelium derived relaxing factor. Br. J. Pharmacol., 102, 331–336. Elgoyhen, B. and Adler-Graschinsky, E. (1989). Diminution by benzodiazepines of the chronotropic responses to noradrenaline in rat isolated atria. Eur. J. Pharmacol., 164, 467–478. Elgoyhen, B., Lorenzo, P. S., Tellez-Iñón, M. T. and Adler-Graschinsky, E. (1992). Relaxant effects of β-carbolines on rat aortic rings. J. Pharmacol. Exp. Ther., 261, 534–539. French, J. F., Rapoport, R. M. and Matlib, M. A. (1989). Possible mechanism of benzodiazepine-induced relaxation of vascular smooth muscle. J. Cardiovasc. Pharmacol., 14, 405–411. Fulton, A. and Burrows, G. D. (1984). Benzodiazepine anxiolytic action and affinities for serotonergic and adrenergic receptors. Prog. Neuro-Psychopharmacol. and Biol. Psychiat., 8, 33–37. Hunkeler, W., Möhler, H., Pieri, L., Polc, P., Bonetti, E. P., Cumin, R., Schaffner, R. and Haefely, W. (1981). Selective antagonists of benzodiazepines. Nature, 290, 514–516. Kazanietz, M. G. and Elgoyhen, A. B. (1990). Relaxant effects of benzodiazepines on uterine rings isolated from estrogen-treated rats. Eur. J. Pharmacol., 185, 231–234. Le Fur, G., Vaucher, N., Perrier, M. L., Flamier, A., Benavides, J., Renault, C., Dubroeucq, M. C., Guérémy, C. and Uzan, A. (1983). Differentiation between two ligands for peripheral benzodiazepine binding sites, [3H]-Ro 5-4864 and [3H]-PK 11195, by thermodynamic studies. Life Sci., 33, 449–457. Raeburn, D., Willer, L. G. and Summer, W. R. (1988). Peripheral type benzodiazepine receptor and airway smooth muscle relaxation. J. Pharmacol. Exp. Ther., 245, 557–562. Schoemaker, H., Boles, R. G., Horst, W. D. and Yamamura, H. I. (1983). Specific high affinity binding sites for [3H]-Ro 5-4864 in rat brain and kidney. J. Pharmacol. Exp. Ther., 225, 61–69. Taniguchi, T., Wang, J. K. T. and Spector, S. (1983). [3H]-diazepam binding sites on rat heart and kidney. Biochem. Pharmacol., 31, 589–590. Van Der Kleijn, E., Vree, T. B., Baars, A. M., Wijsman, R., Edmunds, L. C. and Knop, H. J. (1981). Factors influencing the activity and fate of benzodiazepines in the body. Br. J. Clin. Pharmacol., 11, 85S–98S. Citing Literature Volume13, Issue6December 1993Pages 373-379 ReferencesRelatedInformation

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