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BIBTEX RIS

Zinc Chloride-Promoted Aryl Bromide−Alkyne Cross-Coupling Reactions at Room Temperature

2009; American Chemical Society; Volume: 74; Issue: 22 Linguagem: Inglês

10.1021/jo902015w

ISSN

1520-6904

Autores

Aaron D. Finke, Eric C. Elleby, Michael J. Boyd, Haim Weissman, Jeffrey S. Moore,

Tópico(s)

Sulfur-Based Synthesis Techniques

Resumo

Substoichiometric amounts of ZnCl2 promote the room temperature, Pd/P(t-Bu)3-catalyzed cross-coupling of aryl bromides with alkynes. Pd(I) dimer 1 is demonstrated to be a particularly active precatalyst for this reaction. The reaction is general for a wide variety of aryl bromides.

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