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CTX-M-Type β-Lactamase in Escherichia coli Isolated from Sick Animals in Korea

2009; Mary Ann Liebert, Inc.; Volume: 15; Issue: 2 Linguagem: Inglês

10.1089/mdr.2009.0901

1931-8448

Suk‐Kyung Lim, Hee-Soo Lee, Hyang-Mi Nam, Suk-Chan Jung, You-chan Bae,

Pharmaceutical and Antibiotic Environmental Impacts

About 408 Escherichia coli were isolated from sick farm animals and pets during 2003–2006. Of these isolates, four strains showed resistance to third-generation cephalosporins. The blaCTX-M-14 gene was encountered in three E. coli strains, each of which were isolated from two cows and a dog, respectively, and blaCTX-M-15 was identified in an E. coli isolated from a pig. All blaCTX-M genes were found to be transferred. The pulsed-field gel electrophoresis pattern indicated that the CTX-M-type β-lactamase–producing E. coli isolates were genetically diverse. This study shows the emergence of CTX-M-type β-lactamase–producing E. coli in animals for the first time in Korea. Study results suggest the need for awareness and comprehensive monitoring of extended-spectrum β-lactamases in animals because gene transfer can occur between animals as well as humans.