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Essure hysteroscopic tubal occlusion device for the treatment of hydrosalpinx prior to in vitro fertilization-embryo transfer in patients with a contraindication for laparoscopy

2009; Elsevier BV; Volume: 93; Issue: 4 Linguagem: Inglês

10.1016/j.fertnstert.2008.11.022

1556-5653

Velja Mijatovic, Sebastiaan Veersema, Mark Hans Emanuel, R. Schats, Peter G.A. Hompes,

Endometriosis Research and Treatment

ObjectiveTo investigate the success rate of proximal tubal occlusion with Essure devices in subfertile women with hydrosalpinges, and to observe the results of subsequent treatment with IVF.DesignProspective, single-arm, clinical study.SettingUniversity hospital and teaching hospital.Patient(s)Ten women with uni- or bilateral hydrosalpinges prior to IVF. In all patients laparoscopy was felt to be contraindicated.Intervention(s)Hysteroscopic placement of Essure devices in an office setting.Main Outcome Measure(s)Placement rate, successful proximal tubal occlusion, and pregnancy rate after IVF.Result(s)All patients had successful placement of the Essure devices without any complications. Proximal tubal occlusion was confirmed by hysterosalpingography in 9 out of 10 patients. A 40% ongoing pregnancy rate was achieved with 20% life births after one IVF cycle and/or frozen embryo transfer.Conclusion(s)Proximal occlusion of hydrosalpinges with Essure devices before IVF is a successful treatment for patients with a contraindication for salpingectomy. To investigate the success rate of proximal tubal occlusion with Essure devices in subfertile women with hydrosalpinges, and to observe the results of subsequent treatment with IVF. Prospective, single-arm, clinical study. University hospital and teaching hospital. Ten women with uni- or bilateral hydrosalpinges prior to IVF. In all patients laparoscopy was felt to be contraindicated. Hysteroscopic placement of Essure devices in an office setting. Placement rate, successful proximal tubal occlusion, and pregnancy rate after IVF. All patients had successful placement of the Essure devices without any complications. Proximal tubal occlusion was confirmed by hysterosalpingography in 9 out of 10 patients. A 40% ongoing pregnancy rate was achieved with 20% life births after one IVF cycle and/or frozen embryo transfer. Proximal occlusion of hydrosalpinges with Essure devices before IVF is a successful treatment for patients with a contraindication for salpingectomy.