Efficient Method for the Esterification of Carboxylic Acids with Alcohols Using Di-2-thienyl Carbonate Promoted by DMAP and Iodine
2004; Oxford University Press; Volume: 33; Issue: 8 Linguagem: Inglês
10.1246/cl.2004.968
ISSN1348-0715
AutoresYoshiaki Oohashi, Kentarou Fukumoto, Teruaki Mukaiyama,
Tópico(s)Sulfur-Based Synthesis Techniques
ResumoAbstract Reaction of carboxylic acids with alcohols by using an equimolar amount of di-2-thienyl carbonate (2-DTC) in the presence of a catalytic amount of 4-(dimethylamino)pyridine (DMAP) followed by addition of an equimolar amount of iodine proceeded smoothly to afford the corresponding esters and 2(5H)-thiophenone in good to high yields.
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