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THE EFFECT OF RESERPINE UPON THE RATE OF EGG TRANSPORT IN THE FALLOPIAN TUBE OF THE MOUSE

1967; Bioscientifica; Volume: 13; Issue: 2 Linguagem: Inglês

10.1530/jrf.0.0130345

1741-7899

J. P. Bennett, K. E. Kendle,

Sperm and Testicular Function

Reserpine is a tranquillizer and hypotensive agent (Plummer, Earl, Schneider, Trapold & Barret, 1954) which has been shown to influence uterine smooth muscle activity (Clegg, 1963). The present study was undertaken to investigate the effects of reserpine upon the rate of transport of eggs down the Fallopian tube of the mouse. A stock solution was made by dissolving 300 mg reserpine and 375 mg citric acid in 6 ml benzyl alcohol with gentle warming. A volume of 15 ml ofTween 80 was added. After cooling, the final volume was adjusted to 100 ml with distilled water, and the solution protected from light. This reserpine stock solution was diluted with distilled water immediately before use to adjust the dose volume to 10 ml/kg body weight.