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BIBTEX RIS

5-HT and the immune system

2011; Elsevier BV; Volume: 11; Issue: 1 Linguagem: Inglês

10.1016/j.coph.2011.02.004

ISSN

1471-4973

Autores

Gerard P. Ahern,

Tópico(s)

Receptor Mechanisms and Signaling

Resumo

The classical neurotransmitter, serotonin (5-HT), plays an important role outside of the central nervous system in immune signaling. Here I review recent studies describing 5-HT uptake in dendritic cells and B lymphocytes, 5-HT synthesis in T lymphocytes, and the role of specific 5-HT receptor subtypes in innate and adaptive immune cells. Furthermore, a recent paper describing the immune phenotype of 5-HT deficient mice is discussed.

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