Enantioselective Ring-Opening Reaction of m eso- Epoxides with ArSeH Catalyzed by Heterometallic Ti−Ga−Salen System
2005; American Chemical Society; Volume: 7; Issue: 10 Linguagem: Inglês
10.1021/ol0503034
ISSN1523-7060
AutoresMing‐Hua Yang, Chengjian Zhu, Yuan Fang, Yijun Huang, Yi Pan,
Tópico(s)Sulfur-Based Synthesis Techniques
ResumoThe first example of enantioselective ring-opening reaction of meso-epoxides with aryl selenols to give optically active β-arylseleno alcohol in up to 97% ee was realized, using a chiral Ti−Ga−Salen heterometallic catalyst. A strong synergistic effect of different Lewis acids in the system was exhibited in the catalytic process.
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