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MIDAZOLAM SEDATION REVERSED WITH FLUMAZENIL FOR CARDIOVERSION

1992; Elsevier BV; Volume: 68; Issue: 3 Linguagem: Inglês

10.1093/bja/68.3.303

1471-6771

M. Fennelly, H. POWELL, D. C. Galletly, J.G. WHITWAM,

Cardiovascular Syncope and Autonomic Disorders

Midazolam was used for anaesthesia in 20 patients undergoing cardioversion; 10 received flumazenil, which caused immediate rapid reversal of anaesthesia, and these patients maintained SpO2 greater than 95%, breathing air, within 5-10 min. In contrast, patients in the placebo group were still partially sedated and required oxygen therapy for up to 2 h to maintain a normal SpO2. Arterial pressure, but not heart rate, also was greater in the flumazenil group in the recovery period.