Odynophagia from Aphthous Ulcers of the Pharynx and Esophagus in the Acquired Immunodeficiency Syndrome (AIDS)
1988; American College of Physicians; Volume: 109; Issue: 4 Linguagem: Inglês
10.7326/0003-4819-109-4-338
ISSN1539-3704
Autores Tópico(s)Mycobacterium research and diagnosis
ResumoBrief Reports15 August 1988Odynophagia from Aphthous Ulcers of the Pharynx and Esophagus in the Acquired Immunodeficiency Syndrome (AIDS)Michael C. Bach, MD, August J. Valenti, MD, Douglas A. Howell, MD, Thomas J. Smith, MDMichael C. Bach, MD, August J. Valenti, MD, Douglas A. Howell, MD, Thomas J. Smith, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-109-4-338 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptNonspecific aphthous ulcers of the mouth are common in immunocompetent patients (1). The ulcers are self-limited, rarely progress to involve the hypopharynx or esophagus, and do not usually cause odynophagia. We describe the cases of three patients with the acquired immunodeficiency syndrome (AIDS) who developed severe odynophagia with progressive weight loss, resulting from multiple aphthous ulcers of the hypopharynx and esophagus. No infectious agents could be identified either by biopsy or from culture, and empiric antiviral and antifungal therapy were not effective. Corticosteroid therapy provided prompt and dramatic relief and healing in each patient.Patient 1Patient 1, an 18-year-old...References1. AntoonMiller JR. Aphthous ulcers—a review of the literature on etiology, pathogenesis, diagnosis and treatment. JADA. 1960;101:863-88. Google Scholar2. Weinstein W. The gastrointestinal tract as a target organ. In: Gottlieb MS, moderator. The acquired immunodeficiency syndrome. Ann Intern Med. 1983;99:208-20. MedlineGoogle Scholar3. WeberThornBarrisonUnwin JSIR. Cytomegalovirus colitis and esophageal ulceration in the context of AIDS: Clinical manifestations and preliminary report of treatment with Foscarnet (phosphonoformate). Gut. 1987;28:482-7. CrossrefMedlineGoogle Scholar4. KazlowKumudiniBenkovDischeLeLeiko PSKRN. Esophageal cryptosporidiosis in a child with acquired immune deficiency syndrome. Gastroenterology. 1986;91:1301-3. CrossrefMedlineGoogle Scholar5. RabeneckBoykoMcLeanMcLeodWong LWDWK. Unusual esophageal ulcers containing enveloped virus-like particles in homosexual men. Gastroenterology. 1986;90:1882-9. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: From the Maine Medical Center, Portland, Maine; and the Swedish Hospital Medical Center, Seattle, Washington. For current author addresses, see end of text. 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Winslow, MDRamsay-Hunt Syndrome in a Patient with HIV InfectionFunktionelle und elektrophysiologische Diagnostik bei DysphagieIdiopathic ulcer of the esophagus in the AIDS syndrome: a potential life-threatening complicationSI Units in HematologyThomas J. Spira, MD 15 August 1988Volume 109, Issue 4Page: 338-339KeywordsAIDSAntifungalsAntiviral therapyEsophagusHospital medicineInfectious diseasesMouthPharynxUlcersWeight loss Issue Published: 15 August 1988 PDF DownloadLoading ...
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