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BIBTEX RIS

RNA-Dependent RNA Polymerase Activity in Influenza Virions

1971; National Academy of Sciences; Volume: 68; Issue: 6 Linguagem: Inglês

10.1073/pnas.68.6.1369

ISSN

1091-6490

Autores

Edward E. Penhoet, Henry I. Miller, Michael Doyle, S. P. Blatti,

Tópico(s)

interferon and immune responses

Resumo

An RNA-dependent RNA polymerase activity has been detected in purified preparations of influenza virus. In contrast to the replicase activity induced in influenza-infected cells, the virion-associated enzyme has an absolute requirement for Mn ++ . Most of the RNA synthesized in vitro is complementary to virion RNA.

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