New formal synthesis of (±)-estrone

1990; Issue: 5 Linguagem: Inglês

10.1039/p19900001331

ISSN

2050-8255

Autores

N. M. SUNDER, Prakash A. Patil, N. S. Narasimhan,

Tópico(s)

Microbial Natural Products and Biosynthesis

Resumo

(±)-Estrone is synthesised via Torgov's compound by an AB→ABC→ABCD route. The C-ring is constructed by a new Diels–Alder methodology and the D-ring by a novel cyclopentane annulation reaction from a cyclopropanol precursor.

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