Regulation of steroid-transforming enzymes by endogenous steroids
1983; Pergamon Press; Volume: 19; Issue: 4 Linguagem: Inglês
10.1016/0022-4731(83)91130-5
ISSN1878-2353
Autores Tópico(s)Hormonal Regulation and Hypertension
ResumoThe biosynthesis of C21, C19, and C18 steroids in adrenal, ovary, testisand foeto-placental unit is summarized and the properties of the enzymes involved are described, with particular reference to their substrate specificities and to the possible controlling effects of endogenous steroids. It is concluded that these may exert a considerable regulatory role in vivo in steroid hormone biosynthesis.
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