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Thyrotropin-releasing hormone in the gastrointestinal tract

1977; Elsevier BV; Volume: 79; Issue: 1 Linguagem: Inglês

10.1016/0006-291x(77)90097-3

1090-2104

John E. Morley, Todd J. Garvin, A. EUGENE PEKARY, Jerome M. Hershman,

Growth Hormone and Insulin-like Growth Factors

TRH immunoreactivity has been shown to occur throughout the rat gastrointestinal tract. This immunoreactivity demonstrates parallelism with TRH, is destroyed by fresh human serum, and co-chromatographs with TRH on a Sephadex G-10 column and on a SP Sephadex C-25 column. In addition pancreatic extracts showed bioactivity in a mouse bioassay for TRH.